You describe exactly what I have going on. Tylenol blunts it a little for about 6 hours. I am on Medicinal Marijuana and so far that hasn't helped, but it has only been 2 months and the doctor says it takes 3-4 for helping Neuropathy. The random twitches and nerve pain plus neuropathy in my feet is difficult to cope with. Sorry to hear that Neurologists and a Rheumatologist haven't helped because that was where I was going to turn next.