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Hydroxyurea side effects lessen over time?

Blood Cancers & Disorders | Last Active: Mar 31, 2023 | Replies (36)

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@robert3861

Hi I’m 62 male , was diagnosed 3 months ago with ET and JAK2 positive my platelets were only slightly high the average was 575-600 but she put me on HU 500mg per day it’s been 4 weeks and I’m only down to 430. I take a lot of vitamins and supplements I exercise and run 3 miles a day wondering if this is causing the slow reduction. Do you take and vitamins or supplements?

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Replies to "Hi I’m 62 male , was diagnosed 3 months ago with ET and JAK2 positive my..."

Actually none. I have had no prior health issues or meds what so ever until now. BP, cholesterol and sugar always good. I do exercise and eat pretty healthy but nothing extreme. So I’m on 81 mg aspirin and the HU 500 mg 5X a week. Waiting to see it that’s enough? Now at 56 being hit with this was a shocker!

I am a 61-year-old female. I exercise regularly. My oncologist/dermatologist took me off all supplements except baby aspirin, vitamin D, fiber, and fish oil. I take 1000mg of hydroxyurea daily. My platelets bounce around, but we watch all the counts over time rather than get alarmed by a single blood test (every six weeks right now).

Hi Robert,

Be patient with HU. I am 78 and my hematologist informs me that my goal for platelets is 450 or lower. So you are at my goal for ET JAK2. Remember also that platelets can jump around at times with whatever is happening in your body. It is very fortunate you are not having side effects and I would personally not want to increase the dose to hurry things along,

Best wishes, Eileen