Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?

My dad has had 1 treatment so far. He was in bad shape going into it- the cancer is all in his lymph nodes which are extremely swollen on his neck. He does have some Mets in his bones but those don’t seem to bother him too much. His biggest issue is hydration and nutrition. The last round of chemo he had destroyed his gut. He has lost 70+ lbs in 6 months and struggles everyday to keep down any food and drink. As far as the pluvicto side effects, the only new symptom that came on was diarrhea. It’s heartbreaking to watch. Has anyone experienced a significant improvement in quality of life from plucivto? He desperately wants to see his grandchildren graduate in June but watching him suffer so much is hard. He doesn’t want to
Give up and I’m praying for a miracle

I have heard that Pluvicto now in rare supply these days as government taking away approval due to what it considers to be faults. From what I hear it works so if I were a stage 4 prostate patient I would want this option.
https://www.wsj.com/articles/shortage-of-last-ditch-drug-for-advanced-prostate-cancer-worries-doctors-18de193d

This kinda sucks for those guys who need Pluvicto. I'm not at that point yet. Hopefully Novartis can get approval to start manufacturing in the US very soon. We need as many options as possible.

He was diagnosed with metastatic prostate cancer a little over 4 years ago. He has had several rounds of chemo and radiation. Given his treatment history and disease status the docs thought Pluvicto could keep it from progressing for a while (hopefully through the 6 cycles?). We were very happy for him to be able to try it. The docs aren't sure the pain is related to treatment but given that it started right after treatment, they think it might be so I was curious to find out if any other men have experienced prolonged pain after treatment. Given that it is relatively new, I think they are still learning about it.

I just got my first Pluvicto treatment this past Friday. I have been in stage 4 since 2014. Here's a brief story on my journey. I was diagnosed with Aggressive Prostate cancer at the age of 52, the fall of 2013. My Gleason score was a 9 and my PSA was around 10. I had my surgery to remove my prostate May of 2014. My PSA fell 2 after that. I have bone mets on my spine in the center of my back and neck. The Xgeva shots have worked and the muscle has grown around the fractures and the bones have stabilized. Nothing has spread any further. I have received in this order, Radiation from having my prostate removed, Taxotere chemotherapy, Zytiga and Prednisone, remission for up to almost 4 years, then Xtandi, followed by 13 rounds of Jevtana which just ended this February. March 17 was my first Pluvicto infusion. Through the whole process I have had minimal side effects, the worst being fatigued.

I just got my first Pluvicto treatment this past Friday. I have been in stage 4 since 2014. Here's a brief story on my journey. I was diagnosed with Aggressive Prostate cancer at the age of 52, the fall of 2013. My Gleason score was a 9 and my PSA was around 10. I had my surgery to remove my prostate May of 2014. My PSA fell 2 after that. I have bone mets on my spine in the center of my back and neck. The Xgeva shots have worked and the muscle has grown around the fractures and the bones have stabilized. Nothing has spread any further. I have received in this order, Radiation from having my prostate removed, Taxotere chemotherapy, Zytiga and Prednisone, remission for up to almost 4 years, then Xtandi, followed by 13 rounds of Jevtana which just ended this February. March 17 was my first Pluvicto infusion. Through the whole process I have had minimal side effects, the worst being fatigued.

I am glad you are doing well and hope the Pluvicto does great things for you. May I ask where you are getting treatment? I am considering Pluvicto but hear it is difficult to get.