Hello to everyone. My name is Cynde and I have had stage 4 lung cancer that had spread to my liver but the last ct scan show no evidence of tumor's on liver. I have been on keytruda carbo and taxol, that stopped working after a year changed treatment to Cyramza and taxotere, been doing alright with this but my white count goes down so having to get the Neulasta shot and Arensep to red count. my team has done a fabulous job of keeping me going for 2 years this march 3rd. I am having a big problem with my legs swelling up where I can not bend my leg to my knees. so started rubbing them pretty hard you could hear a popping sound but my leg swelling went down to where I could bend my legs to my knees feet pretty swollen also, now I am having a horrible itch from waist up but no rash, I have tried clairtin benadryl and all the lotions you can get for itching nothing has helped, it is driving me insane so dr, office sent in rx hydroxyzine hcl 10 mg been on that for 2 days sure hope it helps. so far still itch like crazy, has anyone that has been on cyramza and taxotere had this happen to them all I can think is I am allergic to one of these drugs any advice ? thanks and god bless all of us keep strong and ride along!