What a challanging situation for your son. I hope he establiishes a good and trusting patient/DR relationship with his nuerologist, Is he capable of exercise? He may be able to find one specific for Parkinsons and meet others who daily deal with many of the in-common symptoms. Always is good to have individuals who can relate with you. Has he had a recent assesment of his meds? 21 pills a day seems excesive, but if he needs them he needs them. Sometimes we neeed to go back and look at what we are all taking and why. I recently weaned off a pain pill that had clouded my thinking snd reasoning, I didn;t even realise it. My daughter brought my behavior changes to my attention. I hope he can mend from all he is dealing with. AND remember to take care of YOU in all this. Good luck