One out of 8 women get breast cancer and I read that 70% of those cancers are fed by estrogen. I am 8 years out from a breast cancer diagnosis and did 5 years of a med that eliminates all estrogen (adrenals still produce estrogen after menopause). I did not have a genetic link to breast cancer. It is hard to predict who is safe taking hormones, honestly, in my view, but I can understand why people take them.