From Mayo's web site:
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Pain relievers. Over-the-counter pain relievers such as acetaminophen (Tylenol, others), ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve, others) may be helpful. Opioid medications are not recommended, because they can lead to significant side effects and dependence and will worsen the pain over time.

Antidepressants. Duloxetine (Cymbalta) and milnacipran (Savella) may help ease the pain and fatigue associated with fibromyalgia. Your doctor may prescribe amitriptyline or the muscle relaxant cyclobenzaprine to help promote sleep.

Anti-seizure drugs. Medications designed to treat epilepsy are often useful in reducing certain types of pain. Gabapentin (Neurontin) is sometimes helpful in reducing fibromyalgia symptoms, while pregabalin (Lyrica) was the first drug approved by the Food and Drug Administration to treat fibromyalgia.
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I personally have taken Duloxetine for at least 10 years and have taken cyclobenzaprine and pregabalin in the past, but I still have pain issues and occasional times when the pain level greatly escalates for a week. Acetaminophen and ibuprofen were not helpful for me. Now trying naproxen.
I've not found a pain killer (OTC or prescription) that works for FM for me.

As usual, your experience will vary.