@rwinney, @plo99ca, and all... I was first diagnosed with B12 deficiency years ago, quite severe, after developing numbness in my feet and legs, tingling, and neuropathy in my hands as well. I have multiple issues with nerve pain, legs, weakness, and others. I've taken Super B supplements for many years and then began several years ago giving myself B12 injections every 2 weeks. Now, as the testing shows I'm still low, I give shots weekly. I'm having bloodwork this week to see how this area is doing as well as iron and ferritin levels, and all else.

Interestingly, my son, 55 years old, has acute B12 deficiency and must take a very expensive medication in pill form to keep his levels up. This appears to work well for him. So, apparently, we have the dreaded gene for this deficiency and will deal with it ongoing.

My thoughts include poor absorption by the intestines since I have to have frequent iron infusions due to a low ferritin issue. They help immensely.

I'm so glad to find this discussion. I'm finding these issues are becoming more important as I get older. At 76, I need every bit of supplementation out there! God is good. I have Mayo Clinic nearby, wonderful kindness and care, and new friends these last years from Mayo Connect. What joy you have given me, good information, insights, friendships, and a new understanding of my multiple issues. I'm no longer alone in this journey.

Thank you all for your sharing, your encouragement, your love, and your support....be well, and be blessed. elizabeth