@frazer1 I was diagnosed with MGUS when in my early 50's and I just turned 69. I see my hematologist annually for a blood work up and every 3 years I get skeletal x-rays and a dexa scan. This past year when I had my annual exam my hematologist did not order the electrophoresis checking my free light chain kappa/lambda ratio. He said it was an oversight but all my other blood values and X-rays were normal and could wait until my next appointment in October. But he said I could have it done if I wanted to since my kappa/lambda ratio was low .13 (low nl. is .26). the year before. Considering my MGUS was a coincidental finding years ago and I am now approaching the age when Multiple Myeloma usually develops, I might get it done earlier rather than later.
All that being said, I have lived with and monitored my MGUS for many years. I understand with my kappa/lambda ratio dropping I have a greater chance of developing MM than if it were normal-- one study I read said 3% chance per year vs. 1% per year. But with everything else being normal this year I'm just in a holding pattern until something else changes. For all these years with MGUS, I have just tried to take each day as it comes, do what I can to monitor my condition and not worry about tomorrow, because I know that worry adds to stress and stress causes physical changes and problems in my body. Blessings.