Menopause and Neurapothy

Posted by boo55 @boo55, Mar 28, 2019

Hi,
Since around 2015 I have felt some numbness in my feet. BAM! Post menopause, Around Fall of 2019. Terrible numbness in toes and calves with some pain and a diagnosis of small fiber neuropathy. Has anyone else experienced something similar ? Looking for correlations.

Interested in more discussions like this? Go to the Neuropathy Support Group.

I too am newly in menopause. PN occurred about the same time. It has only been 8 months for me but I have had extensive testing done only to dx as ideopathic small fiber PN! I am experiencing weight gain (but that could be from going from playing tennis 4 times a week, walking regularly and working out to practically nothing). I also am experiencing breakouts (acne) like crazy. I’m 53. Could PN be a sign of menopause? That is a great question!! Anyone??

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Weird. I’m 36 but have had one ovary removed which seemed to have thrown my hormones out of balance. I also have PN issues. I started having symptoms of early peri-menopause and like @boo55 said BAM! I thought it was all in my head and the two issues just happened to coincide. I wonder if hormones play a role?

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Hi again ,
Looking online, there have been some studies that are thinking that changing hormone levels may be correlated with PN ,especially estrogen. My Dad had PN also and men have changing hormone levels as they age also. Food for thought. This is just such an icky thing to deal with suddenly every day. 😞

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@boo55, changing hormone levels is listed as a cause...hadn't thought of it before .

NIH - Peripheral Neuropathy Fact Sheet
-- https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Peripheral-Neuropathy-Fact-Sheet

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When my periods stopped the neuropathy started. I even suggested that menopause might be causing it. Of course my neurologist doesn't suspect that, but I always have. I'm 6 years in and the neuropathy seems to be progressing. I brought this up on a thread on FB and there were several women that experienced the same thing with menopause. Now I'm thinking of joining a menopause support group just to pose this question.

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Me too, i started feeling weird sensations in my right leg at 49, with my first hormone disorders,
Now at 52 I can feel the neuropathy all over my body.. Stomach, hands feet, back etc. I was proved to have some denervation by corneal microscope.. But it doesnt say the grade, serious moderate..I have also automomic stuff like night sweating, and terrible fatigue, foggy brain.. Mine the doctors say could be autoinmune mediated, but so far the multiple blood tests done haven't found anything. I take a lot of food suplememts and pregabaline..

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I am a healthy 51 year old in perimenopause with varying symptoms all over my body from the neck down. It started very abruptly the day before Thanksgiving 2022. All of my testing with the exception of B-12 has been negative. My B-12 was low, but has increased significantly with supplements. I also feel that hormones are at least a contributing factor, which my doctors thus far discount. I also had Covid, 2 Covid boosters, and the flu and shingles shot in a 6 month period (4/22 - 10/22), and feel my immune system is in overdrive and out of whack due to this. I feel for everyone else facing this as it has become all consuming.

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I have had neuropathy all of my 51 years due to Ehlers Danlos, but I never realized what it was or that it wasn't a normal thing to have - ha! When I started hormone replacement therapy (pellet), after a 6 month adjustment period, I had a reeeeally bad episode of neuropathy. In trying to figure out if it was a mast cell activation episode or an allergic reaction to something, I realized it was time for my pellet insertion appointment. So, I got on the internet to search for any correlation between the pellet and neuropathy. Could it possibly be that I haven't realized the HRT alleviated the neuropathy??? :O

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@madison2023

I am a healthy 51 year old in perimenopause with varying symptoms all over my body from the neck down. It started very abruptly the day before Thanksgiving 2022. All of my testing with the exception of B-12 has been negative. My B-12 was low, but has increased significantly with supplements. I also feel that hormones are at least a contributing factor, which my doctors thus far discount. I also had Covid, 2 Covid boosters, and the flu and shingles shot in a 6 month period (4/22 - 10/22), and feel my immune system is in overdrive and out of whack due to this. I feel for everyone else facing this as it has become all consuming.

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New publicly available research article on musculoskeletal syndrome of menopause
https://www.tandfonline.com/doi/full/10.1080/13697137.2024.2380363#d1e160

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