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Xtandi and Lupron: Possible drug interaction with spironolactone?
Prostate Cancer | Last Active: Feb 28, 2023 | Replies (5)Comment receiving replies
The main side effect from Xtandi for me is chills and I have not read of any side effects for the heart; however Xtandi is a powerful drug and the interaction with other drugs is something I don’t know about
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I have had heart issues for many years prior to any of my prostate adventures. First stent was placed 22 years ago, and two more stents were placed 2 years ago and started Plavix to protect the stents. Started Lupron plus Xtandi a year ago when my PC metastasized. Although all my doctors have copies of all my meds, neither my cardiologist nor my PC oncologist identified any drug interactions. The potential interaction between Plavix and Xtandi was brought to my attention by my pharmacist when I went to refill my Xtandi. Since then I have been on a half dose of Xtandi and so far it is still working. I don't know anything about Xtandi having an interaction with spironolactone.