GOOGLE; This helps me understand my sister's cancer better
The key difference between SLL and CLL is their location.
With SLL, the accumulation of cancer cells occurs mainly in the lymph nodes but also can also affect the bone marrow.
With CLL (the more common of the two diseases), cancer cells are mainly found in the bloodstream as well as bone marrow.
SLL and CLL were once thought to be different diseases, but are today regarded as different manifestations of the same disease, referred to collectively as CLL/SLL