I have RI as well, diagnosed in August 2022, and using methotrexate and prednisone. The RI symptoms are at bay right now, but I stopped the methotrexate at week 22 for 3 weeks because if intense brain fog. All the ache and pain came back into joints, arms, hands after just 2 weeks - so I started back up again. Dont know what my doc will recommend when I see him again.