Invasive Ductal Carcinoma Stage 2 - Treatment Plan?

Posted by journey99 @journey99, Feb 18, 2023

I am newly diagnosed with IDC Stage 2, 1.3 cm in size. Estrogen Receptor positive, Progesterone positive (1-10%) so not positive enough I have been told, HER2 negative. Ki-67 15%.
I meet with the oncologist, surgeon & radiologist next week. Looking for anyone that has had a similar diagnosis that would share what they had for a treatment plan. Surgery then chemo? Chemo than surgery has been mentioned. What questions I should ask the team? What are things I should consider? Any advice is helpful. I am being told radiation is for sure since lymph nodes are involved. Thank you in advance for sharing experiences and information.

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@anjalima

I am post menopausal and had a unilateral right side mastectomy last February with 2 stage reconstruction ( saline expander inserted at time of surgery and subsequently exchanged for permanent silicone implant) completed in July.
In Jan. 2022, after a “ normal “ mammo and ultrasound in October 2021 I requested an MRI due to a persistent symptom.

BOOM! I was diagnosed with 2 foci ( 2 tumors) unilateral IDC , stage II ( 2 sentinel nodes positive - 5 above those negative) grade II, both ER/PR + HER2- .

The Oncotype indicated that chemo would NOT be beneficial in my case. I am in month 10 of an Aromatase Inhibitor… also known as “hormone therapy “ which is prescribed to limit estrogen production in post menopausal women. I will be taking this for 5-7 years. Similar estrogen limiting therapy is prescribed for pre menopausal women who need to also shut down ovarian estrogen production.

The ONCOTYPE will inform your health team regarding need for ( benefit of) receiving chemo. Since 2015 70% of women with ER/PR + HER2- breast cancer diagnosis have been spared chemo. It’s possible that a non definitive PR + may exclude the option of the ONCOTYPING ( I don’t know).

That said, I understand that if you begin hormone therapy before typing an ONCOTYPE cannot be applied to the biopsy or surgical tissue; it will have been compromised.

A new trial , TAILOR RT is now looking at the need for ( benefit of) radiation therapy. I believe it’s designed to include 1-3 node positive status. It’s still in trial and not definitive. Worth reading about.

My breast surgeons did not recommend radiation but the radiation oncologist did. That’s why I researched the benefit/risk information and found the TAILOR RT trial . My IDC profile fit that trial parameter. One arm of trial was AI alone ( hormone therapy) the other arm was AI plus standard radiation. I opted out of radiation.

Going forward I will get a yearly mammo for healthy breast alternating with a yearly MRI (for both sides ) at 6 mos. Intervals.

It’s a huge learning curve and I am sorry that you have to go through this challenging journey. For me, information is a huge plus. I hope this information has been helpful to you.

Last week I had my annual MRI the same week as my surgery last year. I am ONE YEAR CANCER FREE!

Blessings in the path. 🌸

Jump to this post

Anybody have great pain after lumpectomy & argumentation & lymph dissection
One incision line is draining now
It’s
Been 10
Days and the pain
Is so bad

REPLY
@anjalima

I am post menopausal and had a unilateral right side mastectomy last February with 2 stage reconstruction ( saline expander inserted at time of surgery and subsequently exchanged for permanent silicone implant) completed in July.
In Jan. 2022, after a “ normal “ mammo and ultrasound in October 2021 I requested an MRI due to a persistent symptom.

BOOM! I was diagnosed with 2 foci ( 2 tumors) unilateral IDC , stage II ( 2 sentinel nodes positive - 5 above those negative) grade II, both ER/PR + HER2- .

The Oncotype indicated that chemo would NOT be beneficial in my case. I am in month 10 of an Aromatase Inhibitor… also known as “hormone therapy “ which is prescribed to limit estrogen production in post menopausal women. I will be taking this for 5-7 years. Similar estrogen limiting therapy is prescribed for pre menopausal women who need to also shut down ovarian estrogen production.

The ONCOTYPE will inform your health team regarding need for ( benefit of) receiving chemo. Since 2015 70% of women with ER/PR + HER2- breast cancer diagnosis have been spared chemo. It’s possible that a non definitive PR + may exclude the option of the ONCOTYPING ( I don’t know).

That said, I understand that if you begin hormone therapy before typing an ONCOTYPE cannot be applied to the biopsy or surgical tissue; it will have been compromised.

A new trial , TAILOR RT is now looking at the need for ( benefit of) radiation therapy. I believe it’s designed to include 1-3 node positive status. It’s still in trial and not definitive. Worth reading about.

My breast surgeons did not recommend radiation but the radiation oncologist did. That’s why I researched the benefit/risk information and found the TAILOR RT trial . My IDC profile fit that trial parameter. One arm of trial was AI alone ( hormone therapy) the other arm was AI plus standard radiation. I opted out of radiation.

Going forward I will get a yearly mammo for healthy breast alternating with a yearly MRI (for both sides ) at 6 mos. Intervals.

It’s a huge learning curve and I am sorry that you have to go through this challenging journey. For me, information is a huge plus. I hope this information has been helpful to you.

Last week I had my annual MRI the same week as my surgery last year. I am ONE YEAR CANCER FREE!

Blessings in the path. 🌸

Jump to this post

Blessings to you...hope you remain cancer free in the many years to come.🙏🏼
And thank you for all of your information, advice and just being supportive.

REPLY
@celica

Anybody have great pain after lumpectomy & argumentation & lymph dissection
One incision line is draining now
It’s
Been 10
Days and the pain
Is so bad

Jump to this post

As I have had a unilateral mastectomy I cannot speak to any aftercare if lumpectomy BUT it certainly sounds concerning that you would be in this much pain. After a mastectomy I was able to be relatively comfortable with prescription grade Tylenol or Advil by day two!

Please check back with your surgical team regarding your symptoms and if it were me I would insist on being seen in person so the area can be fully examined.

Best wishes to you for some relief and healing. 🌸

REPLY
@celica

Anybody have great pain after lumpectomy & argumentation & lymph dissection
One incision line is draining now
It’s
Been 10
Days and the pain
Is so bad

Jump to this post

Perhaps there is a secondary cause.

REPLY
@celica

Anybody have great pain after lumpectomy & argumentation & lymph dissection
One incision line is draining now
It’s
Been 10
Days and the pain
Is so bad

Jump to this post

Is there any chance of infection? @celica this is not normal 10 days out. Please call the surgeons office and ask to be seen. Yes there is a chance that there is a reasonable explanation, but you should not be suffering no matter what. Is there redness or heat near the site?

REPLY

I have Stage 2 breast cancer and found out today that I have the Chek 2 gene mutation. Scheduled for lumpectomy in 3 weeks, and wondering if treatment plan should change from this. Anyone else have this situation? If you had this gene, did you change to mastectomy?

REPLY
@journey99

I have Stage 2 breast cancer and found out today that I have the Chek 2 gene mutation. Scheduled for lumpectomy in 3 weeks, and wondering if treatment plan should change from this. Anyone else have this situation? If you had this gene, did you change to mastectomy?

Jump to this post

Are you ILC or IDC? Is it in situ? Are you HER2 + or minus and have they told you the approximate size of the site?

Send a message to your Breast Surgeon with this question. They should be able to answer this.

REPLY
@timely

Are you ILC or IDC? Is it in situ? Are you HER2 + or minus and have they told you the approximate size of the site?

Send a message to your Breast Surgeon with this question. They should be able to answer this.

Jump to this post

This was all in the pathological report that I got after my surgery. You should certainly be able to get this from your surgeon. Important info for you to have. ❤️

REPLY
@journey99

I have Stage 2 breast cancer and found out today that I have the Chek 2 gene mutation. Scheduled for lumpectomy in 3 weeks, and wondering if treatment plan should change from this. Anyone else have this situation? If you had this gene, did you change to mastectomy?

Jump to this post

Hi @journey99, I was wondering if you made a change to your surgical choice with finding out that you had the Chek2 mutation?

REPLY
@colleenyoung

Hi @journey99, I was wondering if you made a change to your surgical choice with finding out that you had the Chek2 mutation?

Jump to this post

Discussed with the doctors and we are moving forward with lumpectomy as planned.

REPLY
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