1. < Breast Cancer

Letrozole: Anyone have muscle pain as a side effect?

Posted by nora305 @nora305, Feb 19, 2023

I was on this medication for ten weeks and then came down with soreness and achiness in my left buttock with referred pain in my left calf. This is not the sharp pain of sciatica. Anybody else have muscle pain symptoms like this?

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polianad22 | @polianad22 | Feb 19, 2023

I would like to know about the side effects.

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timely | @timely | Feb 19, 2023

1) Google the name and all side effects are listed on manufacturer's site.

2) Or request the paper printout that is in the box which the pharmacist takes the bottle out of. This paper printout is same details as above. Some pharmacists do not include this printout with your meds.

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1 reply
windyshores | @windyshores | Feb 19, 2023

Every medication has a longish list of possible side effects. Many of us have taken letrozole for 5 or more years with few or very tolerable side effects. The main issue is loss of bone density, but that can be mitigated.

@mora305 can you get your pain evaluated before deciding it is from letrozole. I am having the same symptom right now in my left hip, radiating, and the doc thinks it is bursitis. I am having an MRI. I am not on letrozole or any aromatase inhibitor: it's been three years since I stopped!

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2 replies
nora305 | @nora305 | Feb 20, 2023
In reply to @windyshores "Every medication has a longish list of possible side effects. Many of us have taken letrozole..." + (show)
@windyshores

Every medication has a longish list of possible side effects. Many of us have taken letrozole for 5 or more years with few or very tolerable side effects. The main issue is loss of bone density, but that can be mitigated.

@mora305 can you get your pain evaluated before deciding it is from letrozole. I am having the same symptom right now in my left hip, radiating, and the doc thinks it is bursitis. I am having an MRI. I am not on letrozole or any aromatase inhibitor: it's been three years since I stopped!

Jump to this post

I am getting an MRI on Thursday to evaluate the cause of the pain. But I think it's interesting that I have never had this pain before and when I started taking letrozole, it showed up.

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nora305 | @nora305 | Feb 20, 2023
In reply to @windyshores "Every medication has a longish list of possible side effects. Many of us have taken letrozole..." + (show)
@windyshores

Every medication has a longish list of possible side effects. Many of us have taken letrozole for 5 or more years with few or very tolerable side effects. The main issue is loss of bone density, but that can be mitigated.

@mora305 can you get your pain evaluated before deciding it is from letrozole. I am having the same symptom right now in my left hip, radiating, and the doc thinks it is bursitis. I am having an MRI. I am not on letrozole or any aromatase inhibitor: it's been three years since I stopped!

Jump to this post

I have already found a longish list of possible side effects for letrozole but that doesn't mean anything to me because I have had so many strange drug reactions in the past. For example, when I received the Pfizer Covid booster, I came down shortly afterwards with a full body rash of itchy hives. It took many weeks for the rash to finally dissipate.

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1 reply
nora305 | @nora305 | Feb 20, 2023
In reply to @timely "1) Google the name and all side effects are listed on manufacturer's site. 2) Or request..." + (show)
@timely

1) Google the name and all side effects are listed on manufacturer's site.

2) Or request the paper printout that is in the box which the pharmacist takes the bottle out of. This paper printout is same details as above. Some pharmacists do not include this printout with your meds.

Jump to this post

As I responded earlier: I have already found and read a longish list of possible side effects for letrozole but that doesn't mean anything to me because I have had so many strange drug reactions in the past. For example, when I received the Pfizer Covid booster, I came down shortly afterwards with a full body rash of itchy hives. It took many weeks for the rash to finally dissipate.

REPLY
windyshores | @windyshores | Feb 20, 2023
In reply to @nora305 "I have already found a longish list of possible side effects for letrozole but that doesn't..." + (show)
@nora305

I have already found a longish list of possible side effects for letrozole but that doesn't mean anything to me because I have had so many strange drug reactions in the past. For example, when I received the Pfizer Covid booster, I came down shortly afterwards with a full body rash of itchy hives. It took many weeks for the rash to finally dissipate.

Jump to this post

@nora305 I also react to most medicines. I tend to make a distinction between "reactions" and "side effects." I tried a generic anastrazole and had a reaction, then tried a generic letrozole and had a reaction, and then tried brand name and was fine. I later found a generic from a different manufacturer that I was fine with.

One thing I am sensitive to is polyethylene glycol, which was in the vaccines and is used in many meds, including ordinary ones like NSAIDs. Maybe you could get tested for that since it seems you may have had an actual allergic reaction.

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lzii01 | @lzii01 | Oct 22 4:51pm

I have been taking letrozole slightly less than a year, and I think I have every side effect possible. A new symptom has just cropped up---upper back cramps. Has anyone else experienced this?

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carrot47 | @carrot47 | Oct 23 10:41am

Igor them in my legs so badly , I had such
Muscle and joint pain and fatique I stoped taking it.
Good luck .

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