I am getting an MRI on Thursday to evaluate the cause of the pain. But I think it's interesting that I have never had this pain before and when I started taking letrozole, it showed up.

I have already found a longish list of possible side effects for letrozole but that doesn't mean anything to me because I have had so many strange drug reactions in the past. For example, when I received the Pfizer Covid booster, I came down shortly afterwards with a full body rash of itchy hives. It took many weeks for the rash to finally dissipate.

@windyshores I did almost 2 weeks off letrozole and no migraines and no other bone pains. It was great. I went on Anastrazole right after Mother’s Day and I initially felt so good with no pain in my legs and very comfortable. 7 days later, I was in the hospital for two days for really strong pain from my gut to my side to my shoulder and my back. It felt like knives. I was treated and the pain subsided on the third day. I picked myself up and moved forward heating my back every day to keep the pain calm. Two weeks later, my back had the pain again right in the middle of my Mahjong game, I could no longer sit upright, so I went home and called my doctor. I was back at the ED. They gave me an IV with the pain medicine and it went away. 8 1/2 hours. They have recommended coming off the Anastrazole, which I had so many hopes for. It is my birthday this weekend. ED recommended not taking the medication so I have to stop until I see my oncologist. It has been almost a year. I have lost a lot of bone; my back has a lot of issues, I have worked hard to get comfortable, but one step forward and many steps back. They had noted it as muscle pain but it is muscle and bone. I have had arthritis for years and finally felt it was in control. Now, I would like to stop the medications because it is hard to sit up, walk, We have a three weeks vacation in August. What would you do?