← Return to Letrozole and TMJ?

Discussion

Letrozole and TMJ?

Breast Cancer | Last Active: Aug 5 2:48pm | Replies (18)

Comment receiving replies
@bloncape

I’m sorry to hear about your problems with TMJ while taking Letrozole. In 2020, after taking 1/2 dose of anastrozole for one month, I began to take a full dose. I had MANY side effects, one of which was TMJ. My quality of life was very poor. Being new to this medicine, I was not aware that an aromatase inhibitor could cause TMJ. My former oncologist did not acknowledge TMJ or most of my other complaints as being caused by anastrozole. I stopped taking the drug after 6 weeks at full dose. Nearly all of the side effects, including TMJ, went away after some time.

Jump to this post


Replies to "I’m sorry to hear about your problems with TMJ while taking Letrozole. In 2020, after taking..."

Hi Bloncape,
I am experiencing the same reaction from my Mayo oncologist. He said TMJ is not a SE. I took 2 AIs and Tamoxifen over the last 10 months. Both of the first 2 times I stopped, the headaches went away. I suspect they will now too as I'm stopping the drug. It's very disappointing.

I, too, went through a serious recurrence of TMJ after being on Letrozole for about 3-4 months. At 6 months now — serious anxiety, insomnia, heart palpitations, and easily bruised skin. I feel fragile physically and emotionally…is this really worth it, I wonder..? Before BC, I was a reasonably fit and healthy 60 year old. Some days now I feel like I’m 80 🙁