From eirrol — I recently found out about R -lipoic acid from Mayo Connect. My kidney doctor agrees that many people have been helped with their neuropathy using it and he has given his ok for me to try, but he says there have been rare cases of it harming the kidneys. So he wants me to have blood work after using it for about 3 weeks. Wish me luck. I will have you folks on Mayo Connect to thank, if it works. I ordered the Pure Encapsulation brand and the R - lipoic acid as mentioned on Mayo Connect, not the Alpha lipoic acid to try to avoid the heart burn. So expensive, but ordering through Amazon so at least will save the shipping charge. There are solutions out there , if we just keep trying.