I have not gotten formal dx yet but will soon I think from neurologist. Im a social worker and am well versed in psych meds. Seroquel is a powerful antipsychotic and can really knock you out and make you a zombie. Not sure why she’s prescribed this (schizophrenia, bipolar? Extreme anger?) while she may have WMD, sounds like it may have progressed to dementia. She needs to see a dementia specialist. I’m not sure where the closest major medical Ctr is but I would try there — and try to see if neurologist there has experience with WMD. Hopefully they could run the appropriate tests and initiate treatment— most important is lifestyle. There may be meds that help. She shouldn’t be alone, both for safety and lack of social engagement. Some combination of friends, family, church folks and certified nursing assistant.