I crush up 150 mg which is about 4%. Mix it with 70% DMSO gel, which is available on Amazon. You don't need a lot of the gel. Just two squirts.Add a couple of drops of water. It dries like water and is not greasy at all.
I've been using the foot and calf application plus I take 25 mg a day. It's been about a week and a half since I started it. Haven't noticed anything yet but wouldn't expect to because nerve damage only reverses 1 mm a day. If I notice anything I promise I will report back.