@edroz01 Hi, hope you're well today.

My fatigue was mainly due to RLS and Sinemet worked but during the wearing-off period I couldn't rest. My sleep was interrupted from about 2-4 AM every morning when I'd have to take another dose and wait for it to take effect. I found relief with the Neupro patch, which is a dopamine agonist and may be less likely to cause dyskinesia. Since I get a continuous dose of medicine, my sleep is not interrupted and I feel a lot less fatigue and brain fog.

In regard to tremors, I'm not aware of anything that eliminates them. Both Sinemet and Neupro decreased my tremors significantly but neither got rid of them entirely.

Hope you can find something that helps with your most troublesome symptoms.

Take care!