Posted by shenriq @shenriq they put me on 1000 mg hydroxyurea only BCB dropped small rate so put me so gave me hydroxyurea 1500 mg and again (lower little) Doctor will lower it mg hydroxyurea 1000 and then Phlebotomy (give little and take it away) I get heart burn with it. Some one said the heart burn isn't from you medication, it's because you have enlarge spleen and liver (it's all squashed and compacted) But I didn't have heart burn until medication hydroxyurea . Medication are pain and come with side- effects. ( Do's and Don't's - hope you find answers) (prayers) Medication are science experiences.