Hi @layala, welcome. That does sound confounding to hear that you are in the early stages of remission, but no answers as to why you might be feeling lousy. I'm tagging fellow CLL-ers like @kegraves @pieter1961 @carl50 @rlybolt @mabfp3 @sandiegostu @annieg87 @teddytwo @raye @shirlpat @alliefair @dimcdee @carl50 @wmisyr @minnesotajim to join this discussion.

Layala, could it "simply" be the side effects of Imbruvica that are making you feel lousy? Common Imbruvica side effects include muscle and bone pain as well as general tiredness. How long will you continue to take Imbruvica?