Side effects with omeprazole/Prilosec use

Posted by blueorca @blueorca, May 5, 2018

i am an 18-year user of daily OTC Prilosec. It does a perfect job of controlling my GERD but I am constantly battling side effects of nutritional deficiencies in iron, B-12, magnesium, etc. For example, my hair is extremely thin and loss of energy is a constant problem. I am looking for specific help in knowing which supplements to take for this and in what doses and formats and on what schedule. All the nutritionists I've found locally are not well-versed in Prilosec use. Is there a medical provider out there who specializes in this? And would they be willing to work with me long distance?

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Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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I have horrible and painful GERD daily. Started in December after I had a cholecystectomy. On PPI now but still painful, now affecting voice with sore throat. Anyone experienced this? I do not want to take the PPI’s.
I am not overweight, do not drink and do not eat fried food, head of bed elevated too, still pain and it is unrelenting.
Anyone tried herbs? Acupuncture?
Ideas?

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Profile picture for marlaxyz @marlaxyz

I hesitate to write this because i am absolutely not an expert and am an experiment of one. With that said I will tell you my experience.

i was on Prilosec (prescription) for years and then there were a series of events and I stopped taking it. Surprise. NO problem. Then I had an endoscopy (for other reasons) and asked the doctor if he thought I should be taking Prilosec and he said he saw no reason. So I have not gone back to it.

What I did do was adjust my diet and stop eating citrus, tomatoes, and other items - i actually forget now because it is all in the past. I DO eat yogurt, cottage cheese, other cheese (not cheddar) peanut butter, meat, cooked (and non cruciferous) vegetables, yams, berries, bananas, other stuff. . I have a whole list somewhere if you want it, just PM me. I created the list by trial and error - if something gave me GERD, out it went.

One take away I came to was the gastroenterologists do like to prescribe Prilosec. If you have something it will probably fix it. I have other problems but Prilosec is not fixing them, still the GI doctor wanted me to take the Prilosec. . All medicines have an affect on our kidneys and livers. I have a sense Prilosec is not a bad medicine any more than any other (I went back to the original research and found it not compelling) ..it is just that all medicines have problems.

BTW - that vinegar. Yikes. NEVER or as Jackie above called it - "acid"

Best to you and good luck-

Val

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I am sorry you are having his problem, sounds much like what I am going through but mine won’t go away and I started on Omenrazole a PPI which hasn’t completely relieved it.
Now having voice evolvement with sore throat.
Have you tried the cider vinegar?

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Profile picture for tk1 @tk1

I have horrible and painful GERD daily. Started in December after I had a cholecystectomy. On PPI now but still painful, now affecting voice with sore throat. Anyone experienced this? I do not want to take the PPI’s.
I am not overweight, do not drink and do not eat fried food, head of bed elevated too, still pain and it is unrelenting.
Anyone tried herbs? Acupuncture?
Ideas?

Jump to this post

I tried acupuncture and it did nothing for me. I think that if you have terrible GERD then it's not enough to try herbs or cider vinegar and the like. Apparently, bile reflux is common after cholecystectomy. See details and treatment possibilities here: https://www.drmalladi.com/acid-reflux-after-gallbladder-removal/
Maybe you also have a hiatal hernia that is keeping the LES open. (I don't know if you've written more details ab out your situation previously, so apologize that I didn't see it.)
You should go to a gastroenterologist and see what they suggest. Maybe they'll do an endoscopy to see the situation. (With the sedation they give, it's a relatively easy procedure.)

REPLY
Profile picture for tk1 @tk1

I have horrible and painful GERD daily. Started in December after I had a cholecystectomy. On PPI now but still painful, now affecting voice with sore throat. Anyone experienced this? I do not want to take the PPI’s.
I am not overweight, do not drink and do not eat fried food, head of bed elevated too, still pain and it is unrelenting.
Anyone tried herbs? Acupuncture?
Ideas?

Jump to this post

Another thing, if it's bile reflux, which is common after cholecystectomy, then the treatment is different than for acid reflux. See a gastroenterologist and see: https://www.mayoclinic.org/diseases-conditions/bile-reflux/diagnosis-treatment/drc-20370121
PPI may not be the right treatment, but if you do need it don't be wary of taking it

REPLY
Profile picture for tk1 @tk1

I have horrible and painful GERD daily. Started in December after I had a cholecystectomy. On PPI now but still painful, now affecting voice with sore throat. Anyone experienced this? I do not want to take the PPI’s.
I am not overweight, do not drink and do not eat fried food, head of bed elevated too, still pain and it is unrelenting.
Anyone tried herbs? Acupuncture?
Ideas?

Jump to this post

HI,
Sorry about your pain.
Call the surgeon's office and (try to) insist on a follow-up appointment. Maybe put it in writing on his patient portal messages. Definitely see a doctor. I suggest starting with your primary care doctor. Sounds like you are doing everything that you should, and it clearly started post-op, so it seems like a surgical foul-up, which they will deny probably. Stick to your guns (your evidence).
My grandmom's remedy: very slowly drink a tall glass of warm water.
Best of luck to you!

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Profile picture for Bonnie @nightngale1998

Hi there: Has anyone had success in weaning off of Omeprazole? I take it for GERD. Thank you in advance!

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Thanks for your advice, I will try the warm water. I am seeing the surgeon next week and fully aware that his defense well we to deny any relationship between the symptoms.

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Profile picture for t98 @t98

Another thing, if it's bile reflux, which is common after cholecystectomy, then the treatment is different than for acid reflux. See a gastroenterologist and see: https://www.mayoclinic.org/diseases-conditions/bile-reflux/diagnosis-treatment/drc-20370121
PPI may not be the right treatment, but if you do need it don't be wary of taking it

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Thank for your response and info sharing.

REPLY
Profile picture for t98 @t98

I tried acupuncture and it did nothing for me. I think that if you have terrible GERD then it's not enough to try herbs or cider vinegar and the like. Apparently, bile reflux is common after cholecystectomy. See details and treatment possibilities here: https://www.drmalladi.com/acid-reflux-after-gallbladder-removal/
Maybe you also have a hiatal hernia that is keeping the LES open. (I don't know if you've written more details ab out your situation previously, so apologize that I didn't see it.)
You should go to a gastroenterologist and see what they suggest. Maybe they'll do an endoscopy to see the situation. (With the sedation they give, it's a relatively easy procedure.)

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Thanks for your response. Had a screening upper GI with colonoscopy August 2022, all was normal, had one last week, said all looked okay but waiting for biopsy results.,,no hiatal hernia, no problems until I had the surgery, none at all. Coleystectomy was for a suspicious polyp found in gallbladder ultrasound. Now I am miserable. Cannot sleep at night due to pain, eating causes pain. Pain has become a constant companion. I am desperate so going to try acupuncture.

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Profile picture for Bonnie @nightngale1998

Thank you for responding, dand48, hopeful33250, Theresa, and destinanna. I still suffer from GERD from a hiatal hernia. I have taken Oemprazole a little over two years and want to get off of the medication because of the associated health issues of poor absorption of key nutrients (D, B12, and calcium are the ones I am familiar with).

My provider, a competent gentleman, has said "hmmmm." I am an RN so am used to doing the research and my own investigation. I have not found evidenced based information / articles on weaning off of Omeprazole. I have heard it can be done and tried to do so but was met with resistance and poor results when I attempted to do so. I switched over to Zantac and the first three days were reasonable and after that it was very uncomfortable).

The celery sounds hopeful and am trying to figure out the mechanism of action for its success. I have tried cider vinegar and it was met with severe cramping.

I am seeking successful scenario's by the valued participants on this board and will do a fair amount of research / experimentation on my own of what works for me. I take responsibility for my nutrition. I am also Lactose intolerant and have a few other sensitivities / intolerances in digestion.I thank you in advance for any additional feedback.

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Thank you for your post. I too am an RN and have just started on this hellish journey. Started omeprazole a few day ago but terrified of it and coming off it. Right now it is not working for me. I am going to stay tuned to your posts and follow your journey. I started acupuncture 2 days ago, there is some literature supporting GERD treatment success. Not sure how to strengthen my gut microbe with this but am taking probiotics.

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Profile picture for tk1 @tk1

I have horrible and painful GERD daily. Started in December after I had a cholecystectomy. On PPI now but still painful, now affecting voice with sore throat. Anyone experienced this? I do not want to take the PPI’s.
I am not overweight, do not drink and do not eat fried food, head of bed elevated too, still pain and it is unrelenting.
Anyone tried herbs? Acupuncture?
Ideas?

Jump to this post

This may or may not help you in any way, but about 6yrs ago +/- there was an article released that said when PPI's first came out, they were not intended to be used on a long term basis, but because of how helpful they were to GERD sufferers, and apparently few side effects, doctors kept their patients on them indefinitely. I like many others was in that group. But then it was written that there actually were some definitely unwanted side effects. PPI's send a signal from your brain to your gut to "cut the acid", And I guess after years of this, its hard to go back to normal. I decided on my own to stop my PPI. ( I am a retired RN) I was so ill that I could not even eat, and lost 20#. My GI doc convinced me to get back on it , which I did. You have to weigh the pros and cons. Thing were going well, and then out of nowhere-LPR

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