There is another type of prolotherapy, PRP or platelet rich plasma. Your blood is taken out in a large syringe, spun to concentrate platelets and then reinjected in the joint (and others if any is left over!). For my daughter's SI joint issues, after years of PT, this worked overnight and lasted 8 years.
You have to meet criteria after screening with imaging to make sure the issue is soft tissue. My daughter has hypermobile joints that "sublux" (move out of place) and tightening things really helped.
Pressing hard on a location with pain tends to ease muscle spasm but not sure how it would address loose ligaments or joints that have shifted slightly . Curious about this. I have learned to press hard on my shoulder to release a muscle there.