Forteo vs. Tymlos: Which did you choose?

I had Reclast. It was a once a year infusion.

The reason Tymlos might be less effective after Forteo, which is a similar med, is different from the reason it might not be as effective after Prolia, which works very differently.

Because Evenity "turbocharges" (saw this term online) bone growth, I have read that it is also more effective to do Tymlos/Forteo then Evenity rather than Evenity then Tymlos/Forteo at least in sequence.

Thank you for reaching out to me. I’ll be happy to check out these links, and hear from others.
That is also what I know about TYMLOS, that detail is attractive to me. I have not been treated for osteoporosis before. Every two years, I went to radiology for bone density tests, each test progressively worse, not reaching osteoporosis til this year. Then I was referred to, Center for Osteoporosis, UCONN Musculoskeletal Institute. Come to find out in my spine I have 1or 2 vertebrae @ 3.4. After a urine test I was told I make bone at a normal rate, but lose it faster than I make it. Due to an unrelated chest X-ray, 2 more vertebrae were detected one crumbling, another almost. That’s my history in a nutshell. Now I’m trying to learn as much as I can. Once I hear back from my PCP, I asked for her opinion of TYMLOS, and want her to be aware I’ll be on it. This next week, I’ll know if my insurance will help with prescription costs, then shortly thereafter, I’ll begin treatment.

I am beginning to understand that the order you take the different meds is important. I was on Fosomax for many years. Have been on a drug holiday also for many years. Now my doc wants me to start on Prolia. I wonder if the reasonTymlos/Forteo were not suggested is because either of these drugs would be better taken after Prolia. Also, would Evenity be better taken before or after Prolia? In the dark about these questions.

I am beginning to understand that the order you take the different meds is important. I was on Fosomax for many years. Have been on a drug holiday also for many years. Now my doc wants me to start on Prolia. I wonder if the reasonTymlos/Forteo were not suggested is because either of these drugs would be better taken after Prolia. Also, would Evenity be better taken before or after Prolia? In the dark about these questions.

My understanding is that the bone building drugs need to be first.

Thank you for your reply. Based on my readings, it is also my understanding. My doctor, however, firmly believes that Prolia is the next best treatment for me. When I asked about Forteo, she said she would only recommend it in extremely rare circumstances.

@louise2023 what are your DEXA scores and do you have any fractures?

Your problem may be insurance coverage, and the policy is misguided in that the bone builders are covered for those who have fractured, have severe scores and/or cannot tolerate first line drugs.

If your scores are bad, you might want a second opinion. My doc won't prescribe Prolia because bone density drops off abruptly if you stop and you have to follow with another med.

I think the other issue is that you have been on Fosamax "for many years." Bone quality issues, dental issues and atypical femur fracture risks go up, I believe, after many years on anti-resorptives, and Prolia is also an anti-resorptive. I would ask your doc about this. It may be that your doc could get insurance to cover Tymlos or Forteo on the basis of your previous Fosamax use.

I had Reclast. It was a once a year infusion.