@dmanduca i share the concern, though since I did Tymlos I might be able to do Evenity afterward. My doc said if my DECA is good enough after 18 months of Tymlos, he will try 1/4 dose Reclast (which like Fosamax is a bisphosphonate) because I react to so many meds. I wil have a lot of water, maybe Tylenol, maybe Benadryl, and a slow infusion. My doc will not prescribe Prolia for me.