When my PN started 6 years ago, heat and cold intolerance happened many times a day, for long periods, with the frozen-to-the-bone feeling in the feet & hands the most frequent and hopelessly painful. I found that in time, Gabapentin helped keep these in very much improved moderation that provides so much relief in comparison to back then. I had a 6 month follow-up with my Neurologist yesterday and ask for advice on how I might handle flare-ups of painful icy cold when it happened, and he said, "I really don't know, maybe heating pads?" Sadly, 6 of the 8 other questions I had written down to ask him, ranging from "Prognosis/Average Expectations for my Condition" to "advice on trying Alpha Lipoic Acid when you have a low blood sugar problem" to "Have I ever been or should be tested for CMT" were answered briefly and simply with just "I don't know". But with this forum, you can learn a lot of tried remedies from experienced folks and can hopefully find something that works for you!