Yes, I get labs done now once a week and the numbers can not go below 5. The docs monitor and will tell me if there is a change to the doseage based on the labs. The med at the high dose sped up my whole body, hands, voice, and caused great anxiety. And there is no treatment for the anxiety so far except camomille tea. My heart rate was sped up too and once measured 120, which is dangerous. I finally saw my cardiologist and she gave me a low dose of Metoprolol to take if the heart rate goes up regularly over 100. But it is lower now from 88-100 on a regular basis. BB