A 5 o'clock meltdown sounds like a medication wearing off. If you are using a 24 hour antihistamine you may need to supplement about 1 hour before that. I find that it helps me to avoid a full on allergy attack if I take a benadryl when exposed to a lot of allergens (hiking, gardening, sanding ..)
Have you tried that? Or changed antihistamines?
Sue

Hi @fab44
So, happy that your surgery worked. I am allergic to too many things, so many sinus infections!
I take my allergy meds twice a day and use fluconase (that was a game changer). I do not use the same allergy meds for more than two years, I rotate the type. My allergies are at their worst in the winter. I agree that it sounds like the meds are wearing off. If you have a 24 hour pill you could cut in half, and take it an hour before your body starts having issues. You should contact your doctor first though, I have pratical experience, not medical knowledge.

To: fab44
Hi there. I am very new to the blogs. But when I read yours, had to respond. I, too h had 2 sinus surgeries. They were a bit helpfu but did not eliminate constant sinus issues & mucus in my throat. Constant throat clearing. Drove family crazy. I am also allergic & was test & found positive for topical allergens. I just became worse over several years & recently finally saw pulmonologist who had a CT scan done & sputum tested. Found MAC or Macrobiotic infection in lungs. This type can be Tuberculosis or Avian bacteria. Mine is non TB. This is a drug resistant bacteria. I Strongly suggest you see a pulmonologist ASAP.