My mother had all of that and it spanned decades. She died of PD at 94 . Her sister had it and her nephews have it and I did mountains of research on GAD having been a counselor. I realized I had that myself and got onto Effexor xr at least 25 years ago. There are papers written now and studies done, on the very real possibility that anxiety disorder is the precursor for PD. Therefore I will never go off Effexor. My two adult children are on it as well, as they both have GAD. My cousins who did not go on it, even though their mother had GAD and minimal PD, and they both now have PD , older one full blown. There is not nearly enough information out there as there should be. Robin Williams suicide due to Lewy Body Dementia from PD, the same type as my mother, was a door opening for so much information as he had severe anxiety as a child, ADHD as well and then treated for depression but not the other two. His story is painful to read but highly informative. The fact that he is Welsh like my mother and her family, was of course not lost on me either. I hope as people are lining up their meds that they include Effexor, designed especially for anxiety , and not as an antidepressant even though thats the category it often sits in!……I distinctly remember my psychiatrist saying “you are about the least depressed person I’ve ever met. You just have Generalized Anxiety Disorder so that what we are just going to treat”. Wise wise man!….It gave me a wonderful ownership of myself!!!