← Return to Low Platelets with Myelodysplastic Syndrome (MDS)

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@loribmt

Hi @shels93, I know the anxiety of an unexplained fever when on chemotherapy. It isn’t uncommon for that to happen several days after the last chemo treatment.

For your husband this is occurring during his off-treatment week and his blood numbers, before the transfusions, were quite low. That is when there is a possibility of a neutropenic fever. There often is no discernible cause but all precautions such as getting him back to the hospital for observation and possibly antibiotics is important. So he’s in the right place.

It looks like the transfusions helped elevate his red blood count and his platelets. But the WBC will have to regenerate on its own. Fairly frequently after Chemo, patients are given a medication to help promote WBC generation such as Neulasta. It can help prevent the possibly of infections due to the low WBC. Do you know if he was given Neulasta?

I’m expecting with some of the blood work his doctors ordered today that they also did a blood culture to check for bacterial infections. Those results can take a few days to return. He may also receive some prophylactic antibiotics if his fever persists.

Wish I had better news for you but this is not uncommon to have an unexplained fever and needing transfusions of RBC and platelets.He should start feeling better as his WBC count starts increasing again. How has he been doing otherwise? Are his doctors encouraged with his treatments?

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Replies to "Hi @shels93, I know the anxiety of an unexplained fever when on chemotherapy. It isn’t uncommon..."

Lori-thank you so much for the fast reply. He has not been given anything (specifically Neulasta per your question), or anything else for that matter. I actually tonight wrote down to ask his oncologist about why this is...I had read that others have been taking Promata /Prednisone/Rituxan for low platelets but he has been prescribed none of that. They did not give him any antibiotics today (or before). They did take two vials of blood (that tbh looked like airplane bottles of alcohol-a moment of levity) and were sending those out for testing. They also had him sign off on getting a transfusion tonight if levels continue to be low. Kicker is we're supposed to see his specialist on Tuesday (he is the MDS Specialist and would handle the BMT) but now we're wondering if that will have to be rescheduled (after waiting 2 months from our initial appointment with him). We were hoping to get perspective on how the doctor thinks he's responding at that appointment. He's been really tired, that is the biggest symptom. He also gets really winded going up stairs. His WBC's were 2.59 on 9-16, 3.57 on 10-25, 4.24 on 10-27, 3.42 on 11-1, 2.46 on 11-8, 2.49 on 11-11, 3.64 on 11-16, 4.45 on 11-18, 5.06 on 11-21, 3.42 on 11-29, 3.33 again on 11-29, and 3.17 on 12-1.

Thank you again so much for this.