Hello @mercator and welcome to Mayo Clinic Connect. I wanted to more quickly connect you with previous comments from members as well as other members too, so you will notice that I have moved your post into an existing discussion on the same topic, which you can find here:

- Immunotherapy - Keytruda for colorectal cancer: https://connect.mayoclinic.org/discussion/immunotherapy-keytryda/

Members @bjs06 @sundance6 and @virgo1952 have been part of this discussion and may be able to share more with you.

Have you shared your fatigue with your oncologist?