I am also on the neuropathy forum, because my original diagnosis was fibromyalgia, but have been found to have small fiber neuropathy. Anyway, I suffer from reflux, with esophageal spasms if I don’t keep it under control. I have a great gastroenterologist who has helped me control that, and my constipation. I take prescription omeprazole, 40mg, every morning. For the constipation, I have settled on Mirilax. I can use it morning and night if needed, and tailor the dose by adding more or less to my water. I also just read a reference to Colon Max on the other forum. I’m going to read about it.
As far as water goes, I’ve always been a big water drinker. With the neuropathy, I carry water with me everywhere. I seem to need a swallow every 30 minutes or so throughout the day. I can put my Miralsx in there. You could do the same with the Metamucil.
I would recommend that you find a liquid that you enjoy - it could be anything - to take your supplements with, and make sure you are hydrated enough for them to work.
I’m going to research that Colon Max!