Your hemo's dosing strategy is interesting, and I might ask mine about that. How often do you have to get labs? Mine are every three months. I am CALR+ and somewhat less likely to clot up than JAK2+ patients.

When I was first diagnosed, it seemed like docs were giving patients huge doses of HU and reducing only if they had terrible side effects. Now doctors try to start off with small doses in hopes of finding the lowest effective dose. I wonder if the incidence of leg ulcers might diminish as doctors lower HU dosing?