Well this is my gang, here. I was just diagnosed (age 64, now one day away from Medicare) with ET/JAK2 after having high platelets since my 30s, with no decisive side effects. (Aside from Visual Migraines which they say COULD be symptoms.) I was always in the 400s to 600s platelet count until a year ago when the numbers climbed and set off other blood counts. So after just monitoring for decades, I was sent to hema/oncology for BMB, etc. (Quite a different attitude these days, as I see people alarmed at a 500 number!) I'm near the 1 million number now, and am guessing I am having symptoms. It's hard to tell if head aches, tiredness and rare dizziness are due to extreme insomnia, though, and that will likely only resolve when I make up my mind about treatment. I am back to oncology next week. If the numbers have climbed again, I don't see much hope for avoiding HU, as flawed an approach to healing as it is. "Dealing," not healing, is what it seems to do. Well, I may be ready to deal. I'm talking to my acupuncturist tomorrow, and in late December with a Mayo doctor. In the meantime, I'm just trying to learn about the disease and ways of coping emotionally and physically. Seems a shame to let all my good habits and confidence crumble in the face of this stupid mutation. My Best to all ET-ers here.