I am 77 and was recently diagnosed with JAK2 ET in September of this year and have had the red feet and ankles. I also have red splotches (for lack of a better word) on the back of my left leg. These are not painful - just unsightly. I have a small level of numbness in both feet and in my left leg. These things are recent. My hematologist/oncologist prescribed hydroxyurea 500 mg daily. I had no side effects the first month. I had a bone marrow biopsy and it was confirmed, that indeed, it was the ET JAK2. My platelets went from around 600 to normal within 10 days of starting the hydroxyurea. I was thinking all was great......then the sores in and on my mouth appeared and my doctor took me off the meds for a 5 day period and I am to start taking the hydroxyurea every other day. It has taken a toll on me - It was difficult to eat and swallow. I still continue with the low dose aspirin which I was already taking when I was first diagnosed. Now I am terrified to go back on a full dose of the hydroxyurea for fear of the mouth sores. This is all so new to me. Has anyone else had problems with sores in their mouth?
Ginger