I new to this connect web site. I have multiple myeloma, osteoporosis and 4 fractures in my back that aren’t really as painful as when first discovered. (One collapsed) I have one issue that I don’t have an answer to. I take 5 Dexamethasone at 5:30am on my Wednesday chemo injection day. Last Wednesday evening I started burning when I urinated. I drank a lot of water. Went to bed but couldn’t sleep. It was still burning. Tried many times to urinate because it kept burning. Only trickled. Finally at 4:00am, I found my OTC AZO, took 2 and I finally fell asleep. I have E Coli I was told and am on Sulfamethoxazole-ole-tmp DDs for 5 days. But yesterday the same thing happened at night. Must of gone to bathroom 6 times, but it still burnt. Took otc AZO again, but just weakened the burning. I’ve already taken half of the Sulfamethoxazole…………. I’m guessing it has something to do with the steroid pills I take all 5 at 5:30am. But ????? It’s Thanksgiving and I’m not going to be able to get an answer today, but I will try to get one Friday. I started chemo in June this year. Any one have the same experience?