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Statins combined with niacin

Neuropathy | Last Active: Dec 5, 2022 | Replies (14)

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@steveny9

Hi,
Yes, that has been one of my concerns: I developed small fiber neuropathy (no pain, just numbness) after taking simvastatin for over 10 years. I side effect I was not aware of. I stopped taking simvastatin 20 mg (which I recently discovered is one of the more least effective of statins and has been in question since 2007) for 3 months but my LDL increased. I switched to Rosuvastatin 10 mg but with lots of hesitation. I want to slow the progression of PN by not taking Rosuvastatin. For 3 months I have been on Rosuvastatin and recently added 500 mg of Niacin. (Yes, I get the flush but if you take a 325 coated enteric aspirin 30 minutes before it reduces the flush. I have to take the aspirin anyway because of have AF).
I like to reduce Rosuvastatin to 5 mg every other day because I read it is has a prolong time of 17 hours. Eventually, I like to take 2.5 mg 3 times a week with niacin in between.
My concern is that Niacin can increase uric acid and glucose.
Question:
1) how many mg of Niacin do you take daily (I read that you need 500 mg or more to be effective.
2) Do you take it daily?
3) Have you been able to reduce your LDL
4) Have you seen an increase in your glucose (specially hba1c levels)?
5) And are you Uric Acid numbers increase
I have to say I am a bit lost of this.
I have now reached out to 4 doctors about adding niacin and none have replied back to me. What is up with that?

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Replies to "Hi, Yes, that has been one of my concerns: I developed small fiber neuropathy (no pain,..."

I take B3 20mg daily. The B3 is just one of the supplements I take for neuropathy. The full list can be found in the following discussion:
-- Have you tried the new Protocol 525 product for neuropathy relief?: https://connect.mayoclinic.org/discussion/have-you-tried-the-new-protocol-525-product-for-neuropathy-relief/

I've been able to control my LDL but I'm still working on it. It was 89 last December but had been as high as 107 prior to that. I have another blood lab coming next week so it will be interesting. The last time my Uric Acid was tested in 2019 it was 4.4 mg/dL which was in the standard range (3.7 - 8.0 mg/dL). It can be a bit confusing. I did recently watch a video that explains the cholesterol panel stuff in an easy to understand way. Might explain why a lot of doctors don't know a lot about it 🙂