Hi @keelin, if prednisone did not help your pain, odds are you do not have PMR. Giant Cell Arteritis, the same disorder that attacks the temporal, ophthalmic and other arteries requires twice the prednisone PMR does. The symptoms include headache, tender scalp, problems with vision, problems chewing, dry cough etc. I had an incredibly stiff neck. I started at 40 mg prednisone a year and a half ago. I've been off prednisone for about six weeks. GCA needs treatment because it can cause blindness or stroke. If your symptoms are not responsive to prednisone and you do not have GCA, it could be malignancy, infection connective tissue disorder or hypothyroidism. (Cecil and Goldman's Textbook of Medicine). I hope you get some answers and some relief!