Hi @bosco 17 Being able to stop the anti-rejection meds would be wonderful for so many transplant patients who are required to take them for life after receiving a new organ.

The clinical study I’d referenced in a previous reply is closed but the good news is that I found more articles relating to on-going studies and currently used techniques that are allowing solid organ transplantees to no longer be dependent on the meds.

Here are a few of the articles I found. It looks very encouraging!
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https://med.umn.edu/news-events/researchers-remove-need-anti-rejection-drugs-transplant-recipients
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https://connect.uclahealth.org/2021/08/04/making-transplants-without-a-lifelong-regimen-of-anti-rejection-drugs-a-reality-at-ucla
health/#:~:text=Eliminating%20the%20need%20for%20ant-rejection%20medication%20Incorporating%20an,the%20host%20and%20donor%20live%20side%20by%20side.

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https://www.nih.gov/news-events/nih-research-matters/organ-transplants-without-life-long-drugs
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https://www.vcuhealth.org/news/end-of-anti-rejection-transplant-drugs-a-clinical-trial-at-hume-lee-hopes-so
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https://leaps.org/new-hope-for-organ-transplantation-life-without-anti-rejection-drugs/particle-3
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https://med.umn.edu/news-events/researchers-remove-need-anti-rejection-drugs-transplant-recipients
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From one of your comments today, I see you’re down to .5mg daily of Tacrolimus. That is a very low dosage already. You were wondering about side effects. Do you feel you are experiencing some from the tacrolimus?