I was confirmed as Case #138 ever diagnosed in America with Mastocytosis. The doctors at Vandy performed biopsies (a colorless mole on my collar bone proved to be a "solid nest of mast cells" and a rash on my right thigh proved to be mast cells that had degranulated or ruptured). Those biopsies indicated I was born with 1,000 times the normal number of mast cells in my skin. I went to Vandy thinking I had mononucleosis (fever, swollen lymph nodes). I thought, hey, while I'm here, I'll show them that "mole" and rash. At that time (and for decades) my symptoms were cutaneous. However, I realize now that I also can attribute many of my respiratory problems to masto--pneumonia, walking pneumonia, double pneumonia, bronchitis, sinus reaction to allergens, swollen lymph nodes. Very sickly child! Almost died of pneumonia as an infant. Absent from school so often I had to learn to count to 100 in one day of kindergarten. My "trigger?" Tobacco smoke and both my parents smoked! Oh, they both had urticaria...

Fast forward to the Wu Flu. After the Pfizer double jab, I suffered eighteen months of chronic diarrhea. Up to nine episodes per day. Doubled my H1 Blocker, doubled my H2 Blocker, added a double dose of another H2 Blocker, took myself to the ER for IV infusion of that newer H2 Blocker. NONE of it helped. Why was I savvy enough to connect my GI distress to masto? Because once, one time only, I missed my dose of Claritin and clear, odorless fluid came gushing out of me later in the day. I am famous for being the most regular person on the planet--even when traveling internationally, I get back "on schedule" in 24 hours at the most. Never a previous problem with either diarrhea or constipation. Missed one Claritin and 12 hours later I had to dash!

With the Pfizer vax, I must also speculate that I was reacting to the polyethylene glycol that is an ingredient in those vaccines. I'd had a short-term reaction to thimerosal a decade or more before but nothing but acute nerve inflammation from a previous nerve injury. That polyethylene glycol? Worth researching...

By the way, an international compilation of data determined "a worldwide spike in food hypersensitivity" after the Covid vaccines. Yes, I think we can translate the words "food hypersensitivity" as "food allergy."

Researched, researched, researched! Learned more about MCAS on Inspire.com. Using the SIGHI chart and other online resources, I put myself on a very restricted low histamine diet. Helped but not the magic bullet. I was desperate, having dropped down to an alarming 115 pounds. Based on my body build (skeletal structure and musculature) that 115 would be like someone my height (5' 5") getting down to 105 pounds!

Researched, researched, researched. One, just one fellow sufferer on Inspire.com had a genius of an Allergist who recommended DAO Enzyme. Not a histamine blocker, DAO Enzyme is a histamine digester. It's supposed to take up to 60 days of regular use to have a positive impact since it can take some time to build up in the GI tract. Me? I was so empty that the DAO Enzyme took up residence and started to work within 24 hours. DRAMATIC improvement in 72 hours. Totally back to normal for over three months now while eating absolutely anything and everything I want, including high histamine foods. My weight? Last time I stepped on the scale, I was at 123. May be up to 125 by now. Not obsessed any longer! Granted, I'm still taking DAO Enzyme, two capsules, with every meal.

So? Point being I am self-diagnosed with MCAS-GI/D. That diagnosis was confirmed by my positive results with DAO Enzyme.

By the way, in the middle of my debilitating journey, I lost so many vitamins, minerals and essential electrolytes that I now have Atrial Fibrillation and the attendant blood clots. Loss of minerals for 18 months was so severe that I now have a broken metatarsal in my left foot despite no acute injury. Since I'm back to normal, I am hoping my regimen of calcium, magnesium, boron, Vitamin D3 and Vitamin K2 will aid in that break healing by Thanksgiving, Christmas at the latest. That A-Fib? Same thing. Hoping a proper mineral balance will aid my heart in calming down. Those blood clots? Currently under control (no longer noticeable) with one baby aspirin every night.

Also, in the middle of my journey, I consulted with an Oncological Hematologist to get tested for Systemic Mastocytosis. Negative! Cause for alarm would be a serum tryptase reading of 20.0 or above. Mine? Only 2.0. Granted, I wasn't in an active "flare" at the time since I had to fast for 36 hours before the appointment just so I could leave the house. So, the results may not be truly revealing. I will say I donated blood recently (yes, I'm feeling that good despite the broken bone). My leukocytes and iron content were just fine.

Oh, ceased taking any H2 Blockers (no longer necessary, maybe never necessary) since they contribute to neurological disorders by inhibiting our body's ability to utilize choline. Choline deficiency is a proven factor in future dementia/Alzheimer's. Could the use of all those OTC antacids (many of which are H2 Blockers) be the reason these neurological conditions have spiked in our country? Something to ponder. By the way, received my Advanced Food Intolerance Labs test results a couple months ago. Sure enough, I was deficient in choline. Now, as mentioned, I'm on zero H2 Blockers and supplementing with choline every day. Can I reverse my mental decline? I don't know but I'll do what I can!

I apologize for my typical verbosity but I pray one nugget of info will be of benefit to one person. If so, may you be blessed with success, health and wealth!