Hi @jbaggi 😊
I am happy to hear that your doc ordered a culture to confirm if it's thrush or something else.
Maybe the culture will come back as "healthy flora" and the recommended treatment will be OTC products. These high dose meds can make your mouth feel and taste awful.
Regarding the rejection, was your routine DSA test done during one of your transplant anniversary visits to Mayo or did your local nephrologist order it? (I don't think I have ever had a DSA test). What does a DSA test measure?
I think I may request it during one of my future visits if it can help identify rejection.
I am very happy to hear you are celebrating your SIX year transplant anniversary and your kidney function tests are looking good...that's great news! It sounds like once your thrush (or mouth issue) is back under control you will be good to go again!
Another good point of getting the culture done is it will come back with both the diagnosis and the recommended med to treat whatever is identified, so you will have extra confidence that the med you take will resolve what you have. That may take away your worry that it feels like it's not resolving.
(Also, make sure to track your Tacronlimis blood levels while you are taking fluconazole, if you are currently taking Tacronlimis as one of your meds. I am pretty sure that Fluconazole can increase Tacronlimis blood levels).