@jerilk - yes for me it hurt every time. I am on the thinner side, so not a lot of fat on my arms or stomach. It swelled every time too, but worth it. I would do it again, but one can only be in Evenity for one year. My year is up, so I am going back to Tymlos, I have been off of Tymlos for a little over 2 years. It worked well for me last time.