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Anyone experience multiple CMV resurgences post kidney transplant?
Transplants | Last Active: Dec 29, 2022 | Replies (107)Comment receiving replies
I had no symptoms per se, but I did feel more tired than usual looking back. My my ALT and AST were 800/1000!!!! They did a biopsy and then steroid treatment in the hospital. Then another biopsy. They put me on Valcyte and another med (I’d have to look it up) until the levels came down- which was about 2 months. That’s when the CMV hit. It went away for about 3 months and now it’s back. Waiting to hear on the latest bloodwork. They have not changed my Tacro in awhile. I’m taking 1.5 am and pm. My levels are around 6. I think they are keeping it low so my kidneys don’t get worse? I haven’t asked.
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Good morning @jp1023 😊
It sounds like it was easy for them to know that it was time for a biopsy with ALT and AST numbers like that...sounds a little scary! I am happy to hear that after hospital steroid treatment and a slight med adjustment, your numbers were back in line in 2 months. Of course, handling the rejection aggressively with high dose immune suppression allows an opportunistic infection like CMV to show up. It is definitely a tightrope balancing act!! 😊
Is your immune suppression meds back to your normal levels now that the rejection is handled? If you are achieving a Tac blood level of 6 with such low doses, I am sure they are happy. My Tac blood target range is also 6 to 8 . It takes 6mg of Envarsus XR for me to achieve a blood level of 6. I take my meds with food to buffer my stomach.
Are you taking Myfortic or Mycophenolate at your original dosage (pre-rejection) with your Tac? If CMV returned, did you start Valcyte again?
I am hoping your current CMV viral load is low and easy to stop with a few weeks of Valcyte treatment again. It sounds like you are very close to things resolving. I am looking forward to hearing about your new blood work too.