Hi 1puttman, I have PN in my feet. All the types of pain that are mentioned show up at times. That being said I tried both. About 8 years ago, I flushed $10,000 down the toilet for stem cells by a pretty successful con artist who has his own radio show in the New York area. As for PRP injections, About 3 years ago, I had my pain management Dr. do it. There are several shots involved and one actually did some damage on the top of my right foot. Must have hit a nerve. It has gotten better over time. In any case, it did nothing for my PN pain, absolutely nothing.