Any research on low-dose naltrexone?

Here’s one study
https://clinicaltrials.gov/ct2/show/NCT05430152

Yes I have talked to my neurologist about this. It has been really helpful for those with autoimmune related conditions and long covid. I know someone who is on it now and says it is a game changer. However, she has a diagnosed autoimmune disorder. But I think it depends on what condition you are treating, how it will affect you. Best of luck to you.

Here are a few more research articles on low-dose naltrexone and COVID.

-- Safety and efficacy of low dose naltrexone in a long covid cohort; an interventional pre-post study:
https://www.sciencedirect.com/science/article/pii/S2666354622000758
-- Repurposing low-dose naltrexone for the prevention and treatment of immunothrombosis in COVID-19:
https://academic.oup.com/ehjcvp/article/8/4/402/6530643
-- Naltrexone a potential therapeutic candidate for COVID-19:
https://www.tandfonline.com/doi/full/10.1080/07391102.2020.1820379

Thank you so much. I can take these to my neurologist to have a good discussion.

I've just started LDN this week. Hopefully, I can give updates as time goes on. I will say, that after several weeks of serious fatigue where I had trouble getting out of bed, I woke this morning with none and was able to get some things done today. It should be too soon with the very small dose I've started with (3/4 mg), so we'll see how the coming days are.

@talford how are you doing? Any updates to share?

@colleenyoung I also started LDN about 5 days ago. I do have an underlying autoimmune condition. It has been up and down because I was having side effects from the starting dose of 1.5 mg. So I am now taking about 0.5 mg without any side effects and am sleeping well. I would say that I am starting to feel less fatigue and more spurts of energy during the day. I also think I am starting to feel a shift in my mood and possibly decreased palpitations, but that is yet to be seen overall. I can provide more updates along the way.

I actually just started 1mgLDN and it has helped tremendously with my brain fog. My overall mood is better and it’s clearing up my skin disorder I have. I’ve had no side effects and will titrate to a higher dose of up to 4mgLDN
Hope this helps

I have started LDN 4 weeks ago. Helps pain, brain fog, sleep. Takes a few weeks to start helping, but better than the essential symptoms. I take 4.5 mg before bed. It does give you weird vivid dreams. There are research paper about LDN helping LC

A patient of mine has had severe symptomes. He reasently had low dose naltraxone and has imoroved amazingly. It's not evidence based, nothing is yet. But I just picked up a dose for muself amd my son.
Will keep you posted! Will be krossing all my fingers and toes for the next weeks.....
Anu of you tried it?