I just found this link after joining the Autoimmune group. I am a 69-year-old woman with rheumatoid arthritis for more than 40 years. My symptoms are well managed with sulfasalazine, methotrexate, celebrex, and I can be as active as I choose to be. Last winter I began having severe chest pain and tightness/squeezing that woke me up in the night. This happened several times a month. Alway when I was sound asleep. The discomfort lasted for several hours.My Primary found nothing with EKG and chest x-ray. My rheumatologist ordered a prescription anti-acid to address issues of GERD. I was symptom-free for several months. Recently, the same experience has been occurring again. In these episodes I have no shortness of breath, radiating pain, sweating, nausea, and my blood pressure and pulse are normal. I am at low risk for heart issues due to no family history, low cholesterol, and low blood pressure. I feel something is not right but I also don’t want to panic. Anyone with a similar history?