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@johnbishop

Can you point to any evidence based information on why you say the skin punch biopsy is inaccurate? It's really the gold standard according to many neurologists for diagnosing neuropathy.

-- 2022 - Role of skin punch biopsy in diagnosis of small fiber neuropathy-A review for the neuropathologist: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=5;spage=329;epage=336;aulast=Narasimhaiah
-- 2009 - Diagnosing Small Fiber Neuropathy Through the Use of Skin Biopsy:
https://practicalneurology.com/articles/2009-oct/PN1009_06-php

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Replies to "Can you point to any evidence based information on why you say the skin punch biopsy..."

My neurologists didn’t recommend having a biopsy and claimed that it is far from being a “gold standard”.

The article below address some of the difficulties with using this test. https://jnnp.bmj.com/content/93/9/915

The table below from another article claims that 30% of people with SFN get normal test results.