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Mycophenolate or Myfortic: Do you have GI side effects?

Transplants | Last Active: Dec 2, 2023 | Replies (54)

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@hello1234

Hi @bosco17 😊
I am a two year post kidney transplant patient that takes Mycophenolate and Tacronlimis as my immune suppression meds. My understanding has been that Myfortic can be offered as a replacement to Mycophenolate when there are GI issues. Have you ever discussed this with your transplant doctor or local doctor? Are these new symptoms?

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Replies to "Hi @bosco17 😊 I am a two year post kidney transplant patient that takes Mycophenolate and..."

Myfortic is not indicated for liver tx patients. It is only approved for kidney transplant patients. However I have spoken to my transplant team and they may due a trial on me with Myfortic. Myfortic is metabolized in the small intestine instead of the stomach like Mycophelonate which is how it reduces stomach issues. My question is this if Mycophelonate ripped up my stomach will Myfortic do the same to my small intestine? The GI issues started about 2-3 years ago when I came up with UC. From then on its be a horror waking up everyday with pain thoughout my GI tract.Quality of life has become very very limited to where I can go and what I could eat. The Drs wanted me to use PPIs first to see if that helps but the long term side effects of PPIs is not good and I cant tolerate them besides that only masks the problem and dosent treat the CAUSE.! Anyhow thanks for your sugestion and that will probably be the way I will go is Myfortic because the only other way is to reduce the dosage of the Mycophelonate which requires close monitoring and carries the risk of rejection! Its a shame because the transplant was a God given gift to me but the medications that we have to take is what will kill us in the end as its the co-morbidities of the meds that cause the problems. Thanks for your suggestion

Does Myfortic have any GI side effects . Does it effect the small intestine?